Steroid Conversions

We use steroids all the time in rheumatology, and it's important to know the potency equivalents of all the drugs we use. Remember the ratio 20:5:4:0.75 and the mnemonic above to remember the potency of different steroids. Hydrocortisone has the least amount of anti-inflammatory property and has the shortest duration of action (about 8 to 12 hours). Dexamethasone has the highest amount of anti-inflammatory property and has the longest duration of action (36 to 72 hours). Prednisone, prednisolone, methylprednisolone, and dexamethasone are intermediate acting.


References:Comparison of systemic glucocorticoid preparations. UpToDate. (2022). Retrieved February 20, 2022, from https://www.uptodate.com/contents/image?imageKey=ENDO%2F64138&topicKey=RHEUM%2F7976&search=steroid+potency+chart&rank=2~150&source=see_linkPublished: February 20, 2022